Grapefruit Juice Diet Stems Weight
Gain in Mice
Fad diets come and go, but might there be something to the ones that involve consuming grapefruit and grapefruit juice? New research suggests that a closer look at grapefruit juice is warranted.
A study published Oct. 8 in the journal PLOS ONE found that mice fed a high-fat diet gained 18 percent less weight when they drank clarified, no-pulp grapefruit juice compared with a control group of mice that drank water. Juice-drinking mice also showed improved levels of glucose, insulin, and a type of fat called triacylglycerol compared with their water-drinking counterparts.
If these findings sound somewhat familiar, it may be because the link between grapefruit juice and weight loss—or just decreased weight gain—has been touted in Hollywood diets before. However, the earlier studies behind those claims were often small, not well controlled, and contradictory, according to nutritional sciences and toxicology professors Andreas Stahl and Joseph Napoli, who led the new research.
This latest work was funded by the California Grapefruit Growers Cooperative, but the Berkeley researchers emphasized that the funders had no control or influence over the study design or research findings. Both Stahl and Napoli said they went into this research with some skepticism.
“I was surprised by the findings,” said Stahl. “We even re-checked the calibration of our glucose sensors, and we got the same results over and over again.”
Napoli added that “we see all sorts of scams about nutrition. But these results, based on controlled experiments, warrant further study of the potential health-promoting properties of grapefruit juice.”