Padmini Rangamani

UC Berkeley Chancellor's Postdoctoral Fellow 2013-2014

Oster Lab
Department of Molecular and Cell Biology
University of California at Berkeley
218 Wellman Hall
Berkeley, CA 94720

Research Summary

I am interested in developing mathematical and computational models for biological processes. I am currently working on building models for transport phenomena (diffusion and viscosity) in membranes. I am also working on modeling lipid membranes using mesoscale variables such as lipid tilt. I am co-advised by Prof. David Steigmann in the Mechanical Engineering department. During the course of my doctoral work with Prof. Ravi Iyengar at the Mount Sinai School of Medicine I focused developing models for understanding the mechanisms driving the relationship between cell shape and size during isotropic cell spreading. My current research is focused on developing mechanochemical models for endocytosis.

* - both authors contributed equally.

  1. Padmini Rangamani, Granville Yuguang Xiong and Ravi Iyengar: Multiscale Modeling of Cell Shape from the Actin Cytoskeleton. Prog. Mol. Biol. Transl. Sci., 2014, 123:143-67

  2. Padmini Rangamani, Ayelet Benjamini, Ashutosh Agrawal, Berend Smit, David Steigmann and George Oster: Small Scale Membrane Mechanics. Biomech. Modeling. Mechanobiol. Oct 2013

  3. Padmini Rangamani, Di Zhang, George Oster and Amy Shen: Lipid Nanotube Formation Driven by Osmotic Pressure. J. R. Soc. Interface, 6 Nov 2013, 10(88):20130637

  4. Padmini Rangamani , Azi Lipshtat, Evren U. Azeloglu, Rhodora Cristina Calizo, Mufeng Hu, Saba Ghassemi, James Hone, Suzanne Scarlata, Susana R. Neves and Ravi Iyengar: Decoding Information in Cell Shape. Cell, 12 Sep 2013, 154(6):1356-69

  5. Padmini Rangamani, Ashutosh Agrawal, Kranthi K. Mandadapu, George Oster and David J. Steigmann: Interaction between surface shape and intra-surface viscous flow on lipid membranes . Biomechanics and Modeling in Mechanobiology, 2013, 12(4):833-845

  6. Padmini Rangamani, Marc-Antoine Fardin, Yuguang Xiong, Azi Lipshtat, Olivier Rossier, Michael P. Sheetz and Ravi Iyengar: Signaling network triggers and membrane physical properties control actin cytoskeleton driven isotropic phase of cell spreading . Biophysical Journal, 2011, 100(4): 845-857

  7. Marc-Antoine Fardin*, Olivier Rossier*, Padmini Rangamani , Phillip Avignan, W. Vougenut, Anurag Mathur, Ravi Iyengar and Michael P. Sheetz: Cell spreading as a hydrodynamic process , Soft Matter, 2010, 6, 4788 - 4799.

  8. Yuguang Xiong*, Padmini Rangamani*, Marc-Antoine Fardin, Benjamin Dubin-Thaler, Azi Lipshtat, Michael P. Sheetz and Ravi Iyengar: Mechanisms controlling cell size and shape during isotropic cell spreading Biophysical Journal, 2010, 98(10):2136-2146

  9. Padmini Rangamani and Ravi Iyengar: Modeling cellular signaling networks , Essays Biochem 2008, 45:83-94

  10. Susana R. Neves, Panayiotis Tsokas, Anamika Sarkar, Elizabeth A.Grace, Padmini Rangamani , James C. Shcaff, Robert D.Blitzer, Ion I.Moraru and Ravi Iyengar Cell shape and negative links in regulatory loops coordinately regulate the propagation of spatial information within signaling networks Cell 2008, 133(4) 666-680

  11. Padmini Rangamani and Ravi Iyengar Modeling spatio-temporal interactions in the cell, Journal of Biosciences 2007, 32(1) 157-167

  12. Padmini Rangamani and Lawrence Sirovich Survival and Apoptotic Pathways Initiated by TNF-α: Modeling and Predictions , Biotechnology and Bioengineering, 2007, 97(5) 1216-1229
Works in Progress
  1. Padmini Rangamani, Kranthi K. Mandadapu and George Oster: Effect of Protein-Induced Spontaneous Curvature on Lipid Flow (submitted to Phys. Rev. Lett.)

  2. Padmini Rangamani, Ravi Iyengar: Computational Modeling of the cytoskeleton: a multiscale approach
Ph.D. 2010 Mount Sinai School of Medicine
M.S. 2005 Georgia Institute of Technology
B.Tech. 2001 Osmania University

Padmini Rangamani       Last modified on Aug 30, 2013