Ph.D. (Nutritional Biochemistry), Massachusetts Institute of Technology
M.D., Yale University School of Medicine
Neese RA, Misell LM, Turner S, Chu A, Kim J, Cesar D, Hoh R, Antelo F, Strawford A, McCune JM, Christiansen M, Hellerstein MK. Measurement in vivo of proliferation rates of slow turnover cells by 2H2O labeling of the deoxyribose moiety of DNA. Proc Natl Acad Sci USA 99(24):15345-50, 2002.
Hellerstein MK, Hoh RA, Hanley MB, Cesar D, Lee D, Neese RA, McCune JM. Subpopulations of long-lived and short-lived T cells in advanced HIV-1 infection. J Clin Invest 112(6):956-66, 2003
Shankaran M, King C, Lee J, Busch R, Wolff M, Hellerstein MK. Discovery of novel hippocampal neurogenic agents by using an in vivo stable isotope labeling technique.J Pharm Exp Ther 2006;319(3):1172-81.
Beysen C, Murphy EJ, McLaughlin T, Riiff T, Lamendola C, Turner HC, Awada M, Turner SM, Reaven G, Hellerstein MK. Whole-body glycolysis measured by the deuterated-glucose disposal test correlates highly with insulin resistance in vivo. Diabetes Care. 2007;30(5):1143-9.
Turner SM, Roy S, Sul HS, Neese RA, Murphy EJ, Samandi W, Roohk DJ, Hellerstein MK. Dissociation between adipose tissue fluxes and lipogenic gene expression in ob/ob mice. Am J Physiol Endocrinol Metab. 2007 ;292(4):E1101-9.
Busch R, Neese R, Voogt J, Awada M, Hayes G, Hellerstein M. Measurement of cell proliferation by heavy water labeling. Nat Protoc. 2007;2(12):3045-57.
Hellerstein MK. Exploiting complexity and the robustness of network architecture for drug discovery. J Pharmacol Exp Ther. 2008;325(1):1-9.
Varady K, Roohk DJ, McEvoy-Hein BK, Gaylinn BD, Thorner MO, Hellerstein MK Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice. FASEB J. 2008