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Our major mission is to work in a highly interactive, multi-disciplinary environment on elucidating the molecular mechanisms of energy homeostasis and obesity-associated disorders. Specifically, current research focuses on the role of fatty acids in the development of diabetes, cancer, cardio-vascular disease and hepatobiliary diseases. Using biochemical, genetic, and imaging technologies we have discovered and characterized a novel family of proteins that regulate fatty acid fluxes and demonstrated that inhibiting specific members of this group can significantly improve body weight, insulin sensitivity, and liver health and thus may lead to the development of novel treatment strategies for obesity-related diseases.

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From left to right:
  1. FATP4 (green) expression in the small intestine
  2. Soleus muscle without insulin stained for caveolin (blue), CD36 (green), and FATP1 (red)
  3. Soleus muscle with insulin stained for caveolin (blue), CD36 (green), and FATP1 (red)



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