The opioids, including morphine, hydrocodone, fetanyl, etc., are alkaloid compounds used as powerful painkillers in human medicine. They can be dangerous, as the body develops tolerance with continued use, they are highly addictive, and an overdose may lead to fatal respiratory depression. Scientists have been working to develop alternative pain killers that equally effective but without the obvious drawbacks.
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bohn etal 2000 manglik etal 2016
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Science searches for an alternative to opioids
